Sarika Katiyar

Introduction: Coherent electromagnetic oscillations in triplet patterns between 6 and 26 megahertz have been detected consistently from temporal scalp and other regions in conscious humans (refs). They are part of the ‘DDG’ (‘dodeconogram’, ref), which consists of 12 orders of frequency oscillations (kilohertz, megahertz, gigahertz, terahertz) from microtubules inside neurons, which appear to underlie the ‘EEG’ (electroencephalogram). During surgical procedures with general anaesthesia the ‘depth’ of the anaesthetic (‘lack’ of consciousness) is often monitored with processed EEG to avoid possible awareness when the patient is intended to be unconscious. For example, the BiSpectral (‘BIS’) monitor gives a single number 0 – 100, with 80-100 indicating awake/conscious, and between 40-60 indicating unconscious/anaesthetized. Methods: We tested the feasibility of megahertz brain monitoring as an index of anesthetic depth compared to BIS .In a clinical study of 40 volunteer patients undergoing gastrointestinal laparoscopic surgeries under propofol anesthesia at BMHRC-Bhopal Hospital, India. We first surveyed, mapped and mitigated dominant sources of noise in the surgical operating room including EM emitters—electrosurgical units (∼100 kHz–5 MHz), infusion pumps, monitors, ISM/RFID bands (13.56 and 27.12 MHz)—and established an IEC 60601-1-2 and FDA-compliant protocol for grounding, shielding, and probe isolation to prevent patient or device interference. In each patient volunteer a BIS electrode was placed across the frontal scalp, and a dielectric resonance probe held against temporal scalp and other cranial regions, connected to a spectrum analyzer set to detect 6–26 MHz. The patients were monitored with both BIS and MHz during 3 phases: 1) pre-induction, patient awake, 2) during propofol infusion, patient unresponsive/unconscious, and 3) post-procedure, awakening. Results: In awake phases 1 and 3, the BIS was within 80-100 and the MHz detector showed triplets with peak at 17 MHz and of 10 -15microvolts. Under propofol anaesthesia in phase 2) the triplets disappeared and were replaced by vertical bursts of activity, with some periods of flatline (similar to burst suppression in EEG, but bursts in megahertz). The BIS value varied between 40 and 60 (anaesthetised /unconscious). Thus, we identified MHz triplets as a ‘Correlate of consciousness’, and vertical MHz bursts as the ‘Correlate of anaesthetic-induced unconsciousness’. Discussion: As microtubules generate MHz triplets, our findings are consistent with anaesthesia research (e.g. Wiest, 2025) that brain microtubules are the target of anaesthetic action, and the biological substrate for consciousness. Further research will evaluate MHz and DDG as monitors of consciousness and anaesthetic depth. References: Singh P, Katiyar S, Tipu S, Banishetty S, Dutta T , Ranjan R, Hameroff S, Bandyopadhyay A. (2025). Meninges act as a gate for EEG & DDG: Only MHz Frequencies can reflect from 14 layers, Defining Consciousness – A Clinical Study. Journal of Multiscale Neuroscience. 4. 64-84. 10.56280/1686004826. 2. Michael C Wiest, A quantum microtubule substrate of consciousness is experimentally supported and solves the binding and epiphenomenalism problems, Neuroscience of Consciousness, Volume 2025, Issue 1, 2025, niaf011, https://doi.org/10.1093/nc/niaf011

Dr Sarika Katiyar is a consultant anaesthesiologist with over 20 years of experience, currently serving at Bhopal Memorial Hospital and Research Centre, a superspeciality hospital in Bhopal, India.

Graduated in 2000 from GR Medical College ,Gwalior. Postgraduation from  BMHRC,Bhopal.Trained instructor for BLS/ACLS .Completed Fellowship in Critical Care Ultrasound in Nov 2025.

Her clinical focus spans cardiac hemodynamics, neurology, and critical care, with a special interest in Critical Care Neurology. She has presented papers at various national and international conferences and has over 20 publications in reputed journals, contributing to advancements in anaesthesia and intensive care.